Natriumfluoried: Verskil tussen weergawes

By hoër dosisse wat gebruik word om osteoporose te behandel, kan suiwer natriumfluoried pyn in die bene en onvolledige stresfrakture veroorsaak indien die dosis te hoog is; dit irriteer ook die maag, en kan selfs maagsere veroorsaak. Stadig-vrygestelde en enteries-bedekte vorms van natriumfluoried veroorsaak nie beduidende maag newe-effekte nie, en veroorsaak minder ernstige en minder dikwelse komplikasies in die skelet.<ref>Murray TM, Ste-Marie LG.&#x20;&#x20;[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1335460/ Prevention and management of osteoporosis: consensus statements from the Scientific Advisory Board of the Osteoporosis Society of Canada. 7. Fluoride therapy for osteoporosis].&#x20;''CMAJ''.&#x20;1996;155(7):949–54.&#x20;[//en.wikipedia.org/wiki/PubMed_Identifier [PubMed|PMID]]&nbsp;[//www.ncbi.nlm.nih.gov/pubmed/8837545 8837545].</ref> In die laer dosisse wat vir waterfluoridering gebruik word, is die enigste duidelike nadelige effek tandfluorose, wat die voorkoms van kinders se tande tydens tandontwikkeling kan verander; dit is meestal nie ernstig nie, en verteenwoordig waarskynlik geen noemenswaardige uitwerking op estetiese voorkoms of openbare gesondheid.<ref>National Health and Medical Research Council (Australia).&#x20;''[http://nhmrc.gov.au/_files_nhmrc/file/publications/synopses/Eh41_Flouridation_PART_A.pdf A systematic review of the efficacy and safety of fluoridation]''&#x20;&#x5B;PDF&#x5D;.&#x20;2007.&#x20;[//en.wikipedia.org/wiki/International_Standard_Book_Number_(identifier) {{ISBN]&nbsp;[//en.wikipedia.org/wiki/Special:BookSources/|1-86496-415-4 1-86496-415-4]}}. Summary: Yeung CA.&#x20;&#x20;A systematic review of the efficacy and safety of fluoridation.&#x20;''Evid Based Dent''.&#x20;2008;9(2):39–43.&#x20;[//en.wikipedia.org/wiki/Digital_object_identifier {{doi]:[https://doi.org/10.1038%2Fsj.ebd.6400578 |10.1038/sj.ebd.6400578]}}.&#x20;[//en.wikipedia.org/wiki/PubMed_Identifier [PubMed|PMID]]&nbsp;[//www.ncbi.nlm.nih.gov/pubmed/18584000 18584000].&#x20;[http://nhmrc.gov.au/_files_nhmrc/file/media/media/rel07/Fluoride_Flyer.pdf Lay summary]: ''NHMRC'', 2007.</ref> Chroniese fluoriedinname van 1 ppm in drinkwater kan by sekere individue fluorose veroorsaak, en 'n blootstelling van 1.7 ppm kan in 30-50% van die populasie fluorose veroorsaak.