John B. O'Brien (13 Desember 1884 – 15 Augustus 1936) was 'n Amerikaanse akteur, regisseur, en skrywer. Hy was bekend vir sy rolle in die rolprente Destiny's Toy (1916), Bab's Diary (1917), Father Tom (1921), en The Handicap (1925).
- 1911: The Infant at Snakeville
- 1914: Imar the Servitor
- 1915: The Foundling
- 1915: Her Shattered Idol
- 1915: The Outcast
- 1916: Destiny's Toy
- 1916: The Big Sister
- 1916: The Eternal Grind
- 1916: The Flying Torpedo
- 1916: The Foundling
- 1916: Hulda from Holland
- 1916: Vanity
- 1917: Bab's Diary
- 1917: Maternity
- 1917: Queen X
- 1917: Souls Triumphant
- 1917: The Buffalo Bill Show
- 1917: Her Sister
- 1917: The Unforseen
- 1917: Mary Lawson's Secret
- 1917: Reputation
- 1917: Daughter of Maryland
- 1918: The Girl and the Judge
- 1918: The Inn of the Blue Moon
- 1918: The Street of Seven Stars
- 1919: Impossible Catherine
- 1919: The Bishop's Emeralds
- 1920: Bride 13
- 1920: Wings of Pride
- 1921: Father Tom
- 1921: Annabelle Lee
- 1921: A Daughter of the Law
- 1921: The Family Closet
- 1921: Lonely Heart
- 1921: Thunder Island
- 1922: The Bride's Play
- 1924: Those Who Dare
- 1925: The Handicap
- 1925: Action Galore
- 1925: Daring Days
- 1925: The Desert Demon
- 1925: The Galloping Jinx
- 1925: The Outlaw's Daughter
- 1925: Reckless Courage
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