Margaret Mayo (19 November 1882 – 25 Februarie 1951) was 'n Amerikaanse skryfster en aktrise. Sy was bekend vir haar rolle in die rolprente Baby Mine (1917), The Poor Boob (1919), Polly of the Circus (1932), en Twin Beds (1942).
- 1914: Behind the Scenes
- 1914: The Jungle
- 1915: The Borrowed Babies
- 1917: Baby Mine
- 1917: Nearly Married
- 1917: Polly of the Circus
- 1919: The Poor Boob
- 1920: Twin Beds
- 1921: The Marriage of William Ashe
- 1928: Baby Mine
- 1929: Twin Beds
- 1932: Polly of the Circus
- 1934: The Life of the Party
- 1942: Twin Beds
- 1952: Säg det med blommor
- 1954: Minäkö isä!