Margaret O'Brien (gebore 15 Januarie 1937) is 'n Amerikaanse aktrise en skryfster. Sy is bekend vir haar rolle in die rolprente Journey for Margaret (1942), Meet Me in St. Louis (1944), The Secret Garden (1949), en Dr. Jekyll and Mr. Hyde (2017).
- 1942: Journey for Margaret
- 1943: Lost Angel
- 1943: Jane Eyre
- 1944: Meet Me in St. Louis
- 1944: The Canterville Ghost
- 1944: Music for Millions
- 1945: Our Vines Have Tender Grapes
- 1946: Bad Bascomb
- 1946: Three Wise Fools
- 1947: The Unfinished Dance
- 1948: Big City
- 1948: Tenth Avenue Angel
- 1949: The Secret Garden
- 1949: Little Women
- 1951: Her First Romance
- 1952: Futari no hitomi
- 1956: Glory
- 1960: Heller in Pink Tights
- 1974: Annabelle Lee
- 1994: Hollywood Hotel
- 1998: Creaturealm: From the Dead
- 2009: Dead in Love
- 2017: Dr. Jekyll and Mr. Hyde
- 2018: Near Myth: The Oskar Knight Story
- 2018: Beverly Hills Christmas II
- 2018: Impact Event
- 2018: Prepper's Grove
- 1955: Hollywood Preview
- 1960: The Comedy Spot
- 1974: A.M. Chicago
- 1995: Private Screenings
- 2000: Astro Royal
- 2016: Bunte Now
- 1960: Maggie
- 1974: Death in Space
- 1994: Homeward Bound
- 2002: ShirleyMania
- 2007: Twinkel, twinkel, kleine ster: Herinneringen uit Hollywood
- 2010: Elf Sparkle and the Special Red Dress
- 1994: Meet Me in St. Louis: The Making of an American Classic